Formation of Cytidine Nucleotides from Uridine Nucleotides by Soluble Mammalian Enzymes: Requirements for Glutamine and Guanosine Nucleotides
نویسندگان
چکیده
منابع مشابه
DNAzyme-mediated catalysis with only guanosine and cytidine nucleotides
Single-stranded DNA molecules have the capacity to adopt catalytically active structures known as DNAzymes, although the fundamental limits of this ability have not been determined. Starting with a parent DNAzyme composed of all four types of standard nucleotides, we conducted a search of the surrounding sequence space to identify functional derivatives with catalytic cores composed of only thr...
متن کاملAccumulation of uridine and cytidine nucleotides in Staphylococcus aureus inhibited by gentian violet.
In 1949 Park and Johnson (1) reported the accumulation of labile phosphate esters in penicillin-inhibited Staphylococcus uureus. Later, the compounds which accumulate were identified as three uridine nucleotides (2). Compound 1 (UDP-GNAclactic)1 contains uridine 5’-pyrophosphate linked to an N-acetylamino sugar substituted in an ether linkage with lactic acid (GNAc-lactic). Compound 2 (UDP-GNAc...
متن کاملUridine nucleotides containing 2, 6-diaminopimelic acid from Escherichia coli.
PARK initially reported z the accumulation of amino acid containing nucleotides in penicillin-treated Staphylococcus aureus. Subsequent work% s has shown that the structure of one of these nucleotides is UDP-GNAc-lactyl-L-Ala-D-Glu-L-Lys-D-Ala-D-Ala. Nucleotides lacking one or more of these amino acids ("incomplete peptides") have also been isolated from this organism. A similar nucleotide cont...
متن کاملAcid-soluble nucleotides in bovine thrombocytes.
In connection with our studies on bovine aplastic anemia (24), it became important to determine the nature and approximate amounts of the major acid-soluble nucleotides in blood cells. A survey of the literature revealed only meager information on nucleotides in human thrombocytes (5-8) and only one report dealing (6) with another specie. The presence of adenosine diphosphate and adenosine trip...
متن کاملStimulation of fluid secretion of malpighian tubules of drosophila melanogaster meig. by cyclic nucleotides of inosine, cytidine, thymidine and uridine
External application of the 3',5'-cyclic monophosphates of inosine, cytidine, uridine and thymidine stimulated the fluid secretion rate (FSR) of Malpighian tubules isolated from Drosophila melanogaster. The evidence suggested that the cyclic nucleotides acted intracellularly in some capacity. Receptors of the 'purinergic' type appeared not to be major contributors to fluid secretion; of three p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1960
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)69544-4